28–30 Nov 2018
US/Central timezone

Using GEANT4-dna-chemistry to Estimate DNA Damage from Radiation: Summary and Challenges

29 Nov 2018, 15:45
25m

Speaker

Dr Alexander Henderson (University of Southern Mississippi)

Description

GEANT4-dna-chemistry is a relatively new part of GEANT4 which allows a particle-in-cell (PIC) like simulation of water electrolysis products in liquid. By applying this to a microscopic geometric model of nuclear DNA we can estimate genetic damage caused by particle radiation. To apply this to macroscopic bodies we have furthered the PIC-like methodology by implementing repeated geometry. With certain limiting assumptions, this can be a resource-friendly alternative to pure PIC methods of simulation. However, in the process we have run across certain difficulties in the current state of GEANT4-dna-chemistry. We will summarize our models, the difficulties encountered, and our work-arounds.

Primary author

Dr Alexander Henderson (University of Southern Mississippi)

Co-authors

Prof. Chris Winstead (University of Southern Mississippi) Prof. Khin Maung Maung (University of Southern Mississippi) Mr William Rogers (University of Southern Mississippi)

Presentation materials