13th Geant4 Space Users Workshop

Session

Biological effects

29 Nov 2018, 15:45

Conveners

Biological effects

• Wade Duvall (Naval Research Laboratory)

17. Using GEANT4-dna-chemistry to Estimate DNA Damage from Radiation: Summary and Challenges

Dr Alexander Henderson (University of Southern Mississippi)

29/11/2018, 15:45

GEANT4-dna-chemistry is a relatively new part of GEANT4 which allows a particle-in-cell (PIC) like simulation of water electrolysis products in liquid. By applying this to a microscopic geometric model of nuclear DNA we can estimate genetic damage caused by particle radiation. To apply this to macroscopic bodies we have furthered the PIC-like methodology by implementing repeated geometry. ...

2. A hybrid method calculating linear energy transfer for intensity modulated proton therapy

Dr Xiaoning Ding (Mayo Clinic Arizona)

29/11/2018, 16:10

Intensity modulated proton therapy (IMPT) is an advance form of proton therapy, in which tumor is irradiated by proton beamlet spot-by-spot and layer-by-layer through controlling the trajectory and energy of a focus beam of protons.1,2 While proton radiobiological effects depend primarily on their physical dose distribution, studies have showed that linear energy transfer (LET) plays an...